Liver pathologies are very often diagnosed by modern doctors. The main problems are associated with impaired metabolic functions of the organ. They develop as a result of infections incurred, prolonged use of certain drugs, permanent contact with toxins, alcohol abuse. Immune pathologies may cause liver disease. To restore health, etiotropic and pathogenetic treatment is carried out. The first one is intended to eliminate the causative agent of the disease, and the second one is aimed at normalizing the organ functions. Hepatoprotectors are effective new generation drug products that restore liver cells, eliminate the consequences of a number of diseases, alcohol addiction. The therapeutic effect depends on the nature and stage of the disease. The duration of treatment with hepatoprotectors is establishned by a doctor.
Types of hepatoprotectors and their principles of action
The most common types of such drug products are:
- Plant-based products — relatively inexpensive; they are prescribed most often. The effect of their use has not been studied thoroughly; more modern and effective formulas are available.
- Products of animal origin — quite effective, but can be hazardous with the active form of hepatitis. Another disadvantage of these agents is a high degree of allergenicity.
- Essential — drugs of this type (phospholipids) restore the liver after alcohol consumption, viral hepatitis, can be used concomitantly with hepatotoxic drugs.
- The evidence base is extensive.
Amino acids — mainly ademetionine, but there are others. Due to the antidepressant effect, they are used in the treatment of affective disorders, alcohol and drug addiction.
- Antioxidants, vitamins — the pathogenesis of these drug products shows their maximum efficacy in cirrhosis, hepatitis. Doctors’ opinions about the efficacy of this drug group vary.
- Ursodeoxycholic acid (UDCA) — the agents are used in the complex treatment of liver pathologies. The list of contraindications is minimal, and UDCA can be taken during pregnancy.
Principles of action for the reviewed types of drug products may vary slightly.
Results of treatment with hepatoprotectors
- improve antitoxic functions of hepatocyte cellular structures;
- arrest active oxidation processes;
- relieve inflammation;
- interfere with the production of connective tissue and prevent fibrosis from developing;
- stimulate the recovery of liver cells.
Contraindications and precautions
There are different points of view regarding the efficacy of hepatoprotectors — some doctors consider them affordable and indispensable drugs, others say that their efficacy is controversial, and the side effects are not harmless. Some patients like to prescribe drugs to themselves, which further aggravates the situation. It is important to track negative individual responses that can occur, choose non-toxic agents and strictly follow the doctor’s instructions. With a competent approach to therapy, state of health will improve, and the quality of life will improve as well.